Skip to main content
. 2017 Aug 4;12(8):e0182646. doi: 10.1371/journal.pone.0182646

Fig 6. GM-CSF deficiency enhances the pDC compartment.

Fig 6

(a) Quantification of pDC in skin draining lymph nodes (LN) and spleen (CD45+Siglec-H+, CD11cint) in healthy wild-type (Wt n = 4) and GM-CSF-/- (n = 4) mice without prior IMQ application. Cells were analyzed by flow cytometry and normalized to counting beads. (b) Representative Siglec-H staining (red) in PFA-fixated spleens of Wt and GM-CSF-/- mice (right). The graph shows mean values ± SEM. *p-value<0.05, **p-value<0.01 compared with control group as determined by the Mann-Whitney-U-Test. Scale bars equal 400 μm.