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. Author manuscript; available in PMC: 2017 Aug 4.
Published in final edited form as: Sci Transl Med. 2017 May 17;9(390):eaah5084. doi: 10.1126/scitranslmed.aah5084

Fig. 5. BET bromodomain inhibition does not suppress physiologic cardiac hypertrophy in response to chronic endurance exercise training.

Fig. 5

(A) Schematic of swimming protocol. (B) Gravimetry; heart weight/body weight ratio on day 35 (n = 7). (C) Representative LV cross sections stained with WGA with quantification of mean cardiomyocyte cell area shown at the right (n = 5). Scale bars, 20 µm. (D) Echocardiographic LV ejection fraction on day 35 (n = 7). (E) qRT-PCR for indicated genes in mouse LV tissue (n= 5). For (B) to (E), *P < 0.05, **P < 0.01, ***P < 0.001 for indicated comparisons. No statistically significant JQ1 effect was observed. Data are shown as means ± SEM.