Table 1.
p27 expression | Normal Weight-Luteal Endometrium, n (%) | Normal Weight-Follicular Endometrium, n (%) | Obese-Follicular Endometrium, n (%) | Obese Endometrial CAH, n (%) | Obese-Endometrial Carcinoma Grade 1, n (%) |
---|---|---|---|---|---|
Intact | 4 (67%)* | 1 (7%) | 10 (21%) | 1 (9%) | 1 (11%) |
Slightly Reduced | 2 (33%) | 9 (64%) | 16 (34%) | 2 (18%) | 0 (0%) |
Moderately Reduced | 0 (0%) | 4 (29%) | 12 (26%) | 0 (0%) | 0 (0%) |
Severely Reduced | 0 (0%) | 0 (0%) | 9 (19%) | 8 (73%)** | 8 (89%)*** |
No. samples | 6 | 14 | 47 | 11 | 9 |
Fishers exact test is significant for intact p27 expression in normal weight-luteal endometrium as compared to normal weight-follicular endometrium, obese-follicular endometrium, obese-endometrial CAH and obese-EC grade 1at the p<0.05 level.
Fishers exact test is significant for severely reduced p27 expression in normal weight luteal endometrium as compared to obese endometrial CAH and obese EC at the p<0.025 level.
Fishers exact test is significant for severely reduced p27 expression in normal weight follicular endometrium as compared to obese endometrial CAH and obese EC at the p<0.001 level.