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. 2017 Aug 4;3(8):e1700606. doi: 10.1126/sciadv.1700606

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Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

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Fig. 4 — The interspecies difference in cellular dry mass is automatically recognized and used for screening of anthrax spores. (A to C) The activation of the “anthrax neuron” at the output layer shows a strong correlation with dry mass. a.u., arbitrary units. (D) Dry mass of individual Bacillus spores calculated from the quantitative phase images. (E) Computationally disabling the dry mass information significantly impairs the performance of HoloConvNet. Dry mass alone is not enough for full performance as well. Data in (D) are presented as box-and-whisker plots displaying median and interquartile ranges. The error bars in (E) indicate the SD calculated from 10 classification models with different random initializations.