Fig 2. A 43-year-old woman with a gastrointestinal stromal tumor.

a: Conventional trans-abdominal ultrasound with oral contrast agent showed a lobulated heterogeneous hypoechoic lesion (calipers) located in antrum of stomach, a hyper-echoic calcification plaque could be detected inside of the tumor. b: DCUS showed a ring-like hyper-enhancement (arrow) and heterogeneous hyper-enhanced inside of the lesion. c,d: Microscopic certificated the calcification in GIST (arrow in c)and fascicular proliferation of spindle-shaped cells.(d)(hematoxylin and eosin, × 200). e: Time-intensity curve depicted the lesion (red line) have higher PI and faster AT, TTP than surrounding tissue (yellow), final pathology result classified this GIST into high-risk category.