Table 3.
Univariate relationship between waitlisted patient and donor characteristics and outcomes of kidney offers
| Characteristics | N | Transplant No. (%) | Reason for Offer Refusal, No. of Offers (%) | |||||
|---|---|---|---|---|---|---|---|---|
| Donor-Related | Bypass | Recipient-Related | Histocompatibility | Program | Other | |||
| Waitlisted patient characteristics | ||||||||
| Age, yr | ||||||||
| ≤25 | 272,425 | 1998 (0.7) | 115,705 (42.5) | 125,342 (46.0) | 4569 (1.7) | 6030 (2.2) | 1022 (0.4) | 17,759 (6.5) |
| 26–45 | 2,044,703 | 14,854 (0.7) | 890,490 (43.6) | 925,077 (45.2) | 39,928 (2.0) | 39,403 (1.9) | 7785 (0.4) | 127,166 (6.2) |
| 46–60 | 3,064,007 | 20,631 (0.7) | 1,387,107 (45.3) | 1,364,201 (44.5) | 61,939 (2.0) | 36,612 (1.2) | 12,477 (0.4) | 181,040 (5.9) |
| >60 | 1,756,696 | 11,953 (0.7) | 838,281 (47.7) | 752,152 (42.8) | 35,018 (2.0) | 14,556 (0.8) | 7718 (0.4) | 97,018 (5.5) |
| Race/ethnicity | ||||||||
| White | 2,677,278 | 22,144 (0.8) | 1,250,673 (46.7) | 1,156,771 (43.2) | 50,425 (1.9) | 33,722 (1.3) | 11,047 (0.4) | 152,569 (5.7) |
| Black | 2,414,103 | 16,513 (0.7) | 1,116,771 (46.3) | 1,041,417 (43.1) | 55,045 (2.3) | 39,335 (1.6) | 9914 (0.4) | 135,108 (5.6) |
| Hispanic | 1,473,346 | 7015 (0.5) | 616,690 (41.9) | 704,587 (47.8) | 23,816 (1.6) | 16,806 (1.1) | 5334 (0.4) | 99,098 (6.7) |
| Other | 573,104 | 3764 (0.7) | 247,449 (43.2) | 264,097 (46.1) | 12,141 (2.1) | 6738 (1.2) | 2707 (0.5) | 36,208 (6.3) |
| Sex | ||||||||
| Female | 2,550,879 | 19,799 (0.8) | 1,139,016 (44.7) | 1,125,168 (44.1) | 54,987 (2.2) | 50,052 (2.0) | 10,424 (0.4) | 151,433 (5.9) |
| Male | 4,586,952 | 29,637 (0.7) | 2,092,567 (45.6) | 2,041,604 (44.5) | 86,467 (1.9) | 46,549 (1.0) | 18,578 (0.4) | 271,550 (5.9) |
| Cause of ESRD | ||||||||
| Hypertension | 1,825,703 | 12,175 (0.7) | 836,891 (45.8) | 801,214 (43.9) | 38,273 (2.1) | 21,390 (1.2) | 7686 (0.4) | 108,074 (5.9) |
| Diabetes | 2,245,194 | 12,697 (0.6) | 1,022,537 (45.5) | 1,012,989 (45.1) | 40,848 (1.8) | 16,197 (0.7) | 9084 (0.4) | 130,842 (5.8) |
| GN | 859,860 | 6612 (0.8) | 380,199 (44.2) | 393,008 (45.7) | 13,736 (1.6) | 10,296 (1.2) | 3499 (0.4) | 52,510 (6.1) |
| Other | 2,207,074 | 17,952 (0.8) | 991,956 (44.9) | 959,561 (43.5) | 48,597 (2.2) | 48,718 (2.2) | 8733 (0.4) | 131,557 (6.0) |
| Body mass index, kg/m2 | ||||||||
| <18.5 | 134,883 | 1126 (0.8) | 60,164 (44.6) | 58,898 (43.7) | 3243 (2.4) | 2759 (2.1) | 621 (0.5) | 8075 (6.0) |
| 18.5–24.9 | 1,916,567 | 14,763 (0.8) | 852,346 (44.5) | 847,563 (44.2) | 42,522 (2.2) | 34,827 (1.8) | 8252 (0.4) | 116,294 (6.1) |
| 25–29.9 | 2,407,905 | 16,478 (0.7) | 1,086,561 (45.1) | 1,076,541 (44.7) | 45,066 (1.9) | 29,646 (1.2) | 9762 (0.4) | 143,851 (6.0) |
| ≥30 | 2,678,476 | 17,069 (0.6) | 1,232,515 (46.0) | 1,183,770 (44.2) | 50,623 (1.9) | 29,369 (1.1) | 10,367 (0.4) | 154,763 (5.8) |
| Panel reactive antibodies, % | ||||||||
| 0 | 5,124,898 | 30,397 (0.6) | 2,358,703 (46.0) | 2,282,876 (44.5) | 97,264 (1.9) | 31,153 (0.6) | 20,751 (0.4) | 303,754 (5.9) |
| 1–20 | 630,440 | 3868 (0.6) | 282,053 (44.7) | 290,128 (46.0) | 9878 (1.6) | 5171 (0.8) | 2557 (0.4) | 36,785 (5.8) |
| 21–80 | 933,274 | 7743 (0.8) | 413,427 (44.3) | 414,001 (44.4) | 19,657 (2.1) | 17,995 (1.9) | 3745 (0.4) | 56,706 (6.1) |
| >80 | 449,219 | 7428 (1.7) | 177,400 (39.5) | 179,767 (40.0) | 14,655 (3.3) | 42,282 (9.4) | 1949 (0.4) | 25,738 (5.7) |
| Donor characteristics | ||||||||
| Age, yr | ||||||||
| ≤25 | 1,786,246 | 12,155 (0.7) | 680,286 (38.1) | 917,842 (52.4) | 28,128 (1.6) | 28,335 (1.6) | 5327 (0.3) | 114,173 (6.4) |
| 26–45 | 2,291,158 | 16,169 (0.7) | 911,283 (39.8) | 1,101,819 (48.0) | 43,058 (1.9) | 32,159 (1.4) | 7585 (0.3) | 179,085 (7.8) |
| 46–60 | 2,308,780 | 16,590 (0.7) | 1,194,191 (51.7) | 896,750 (38.8) | 49,716 (2.2) | 29,222 (1.3) | 11,578 (0.5) | 110,733 (4.8) |
| >60 | 751,647 | 4522 (0.6) | 445,823 (59.3) | 250,361 (33.3) | 20,552 (2.7) | 6885 (0.9) | 4512 (0.6) | 18,992 (2.5) |
| Race/ethnicity | ||||||||
| White | 4,647,942 | 34,207 (0.7) | 2,150,083 (46.3) | 2,070,482 (44.5) | 81,711 (1.8) | 58,619 (1.3) | 19,651 (0.4) | 233,189 (5.0) |
| Black | 1,096,086 | 6844 (0.6) | 504,678 (46.0) | 472,082 (43.1) | 26,947 (2.5) | 16,269 (1.5) | 3450 (0.3) | 65,816 (6.0) |
| Hispanic | 1,166,205 | 6555 (0.6) | 462,689 (39.7) | 536,049 (46.0) | 26,276 (2.3) | 18,897 (1.6) | 4335 (0.4) | 111,404 (9.6) |
| Other | 227,598 | 1830 (0.8) | 114,133 (50.2) | 88,159 (38.7) | 6520 (2.9) | 2816 (1.2) | 1566 (0.7) | 12,574 (5.5) |
| Sex | ||||||||
| Female | 2,766,595 | 19,968 (0.7) | 1,317,442 (47.6) | 1,164,028 (42.1) | 57,022 (2.1) | 38,343 (1.4) | 13,585 (0.5) | 156,207 (5.7) |
| Male | 4,371,236 | 29,468 (0.7) | 1,914,141 (43.8) | 2,002,744 (45.8) | 84,432 (1.9) | 58,258 (1.3) | 15,417 (0.4) | 266,776 (6.1) |
| Creatinine, mg/dl | ||||||||
| <1.0 | 2,940,673 | 23,944 (0.8) | 1,245,287 (42.4) | 1,368,411 (46.5) | 61,783 (2.1) | 41,467 (1.4) | 13,848 (0.5) | 185,933 (6.3) |
| 1.0–1.5 | 2,131,043 | 15,666 (0.7) | 842,420 (39.5) | 1,038,867 (48.8) | 42,120 (2.0) | 31,846 (1.5) | 8209 (0.4) | 151,915 (7.1) |
| >1.5 | 2,066,115 | 9826 (0.5) | 1,143,876 (55.4) | 759,494 (36.8) | 37,551 (1.8) | 23,288 (1.1) | 6945 (0.3) | 85,135 (4.1) |
| Hypertension | ||||||||
| Yes | 2,492,647 | 14,896 (0.6) | 1,342,057 (53.8) | 968,470 (38.9) | 51,700 (2.1) | 24,868 (1.0) | 9814 (0.4) | 80,842 (3.2) |
| No | 4,645,184 | 34,540 (0.7) | 1,889,526 (40.7) | 2,198,302 (47.3) | 89,754 (1.9) | 71,733 (1.5) | 19,188 (0.4) | 342,141 (7.4) |
| Diabetes | ||||||||
| Yes | 767,404 | 3750 (0.5) | 458,863 (59.8) | 251,887 (32.8) | 16,536 (2.2) | 7582 (1.0) | 2276 (0.3) | 26,510 (3.5) |
| No | 6,370,427 | 45,686 (0.7) | 2,772,720 (43.5) | 2,914,885 (45.8) | 124,918 (2.0) | 89,019 (1.4) | 26,726 (0.4) | 396,473 (6.2) |
| Cerebrovascular accident | ||||||||
| Yes | 2,507,248 | 17,984 (0.7) | 1,273,700 (50.8) | 989,225 (39.5) | 59,254 (2.4) | 33,654 (1.3) | 12,965 (0.5) | 120,466 (4.8) |
| No | 4,630,583 | 31,452 (0.7) | 1,957,883 (42.3) | 2,177,547 (47.0) | 82,200 (1.8) | 62,947 (1.4) | 16,037 (0.4) | 302,517 (6.5) |
| Cardiac death | ||||||||
| Yes | 1,011,936 | 7073 (0.7) | 550,474 (54.4) | 377,848 (37.3) | 17,171 (1.7) | 13,609 (1.3) | 4973 (0.5) | 40,788 (4.0) |
| No | 6,125,895 | 42,363 (0.7) | 2,681,109 (43.8) | 2,788,924 (45.5) | 124,283 (2.0) | 82,992 (1.4) | 24,029 (0.4) | 382,195 (6.2) |
| Number of offers (quintiles) | ||||||||
| 0–182 | 1,422,885 | 41,829 (2.9) | 867,025 (60.9) | 278,620 (19.6) | 88,151 (6.2) | 76,787 (5.4) | 9206 (0.7) | 61,267 (4.3) |
| 183–575 | 1,430,312 | 3319 (0.2) | 880,864 (61.6) | 446,095 (31.2) | 23,375 (1.6) | 10,805 (0.8) | 5942 (0.4) | 59,912 (4.2) |
| 576–1376 | 1,429,288 | 2290 (0.2) | 778,881 (54.5) | 547,366 (38.3) | 19,648 (1.4) | 6325 (0.4) | 5991 (0.4) | 68,787 (4.8) |
| 1377–3648 | 1,427,728 | 1503 (0.1) | 542,679 (38.0) | 776,688 (54.4) | 9157 (0.6) | 2244 (0.2) | 5933 (0.4) | 89,524 (6.3) |
| ≥3649 | 1,427,618 | 495 (0.03) | 162,134 (11.4) | 1,118,003 (78.3) | 1123 (0.08) | 440 (0.03) | 1930 (0.1) | 143,493 (10.1) |