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Empagliflozin was associated with improved renal outcomes compared to placebo. (A) Estimates of the probability of the first occurrence of the prespecified composite renal outcomes defined as incident or worsening nephropathy. (B) Estimates of the probability of the post hoc renal composite outcomes defined as doubling of serum creatinine level, death from renal disease, or requirement of RRT. Hazard ratios shown are from Cox regression analysis (35). 95% CI, 95% confidence interval.
