Table 2.
Associations of era of home hemodialysis initiation with all-cause mortality, technique failure, and the composite of death and technique failure
| Death | Technique Failure | Death and Technique Failure | ||||
|---|---|---|---|---|---|---|
| Incident Cohort Period | Events | Event Rates/100 Patient-Yr | Events | Event Rates/100 Patient-Yr | Events | Event Rates/100 Patient-Yr |
| 1996–2002 | 51 | 7.3 | 74 | 12.0 | 125 | 19.3 |
| 2003–2007 (ref) | 127 | 7.9 | 158 | 9.5 | 285 | 17.4 |
| 2008–2012 | 91 | 5.5 | 271 | 16.8 | 362 | 22.3 |
| Unadjusted Hazard Ratio (95% CI) | ||||||
| Overall | ||||||
| 1996–2002 | 0.94 (0.68 to 1.31) | 1.10 (0.93 to 1.45) | 1.03 (0.83 to 1.27) | |||
| 2003–2007 (ref) | 1 | 1 | 1 | |||
| 2008–2012 | 0.75 (0.56 to 0.99) | 1.51 (1.23 to 1.86) | 1.19 (1.01 to 1.40) | |||
| Adjusted Hazard Ratio (95% CI) | ||||||
| Overalla | ||||||
| 1996–2002 | 0.67 (0.38 to 1.21) | 1.39 (0.78 to 2.46) | 1.11 (0.71 to 1.74) | |||
| 2003–2007 (ref) | 1 | 1 | 1 | |||
| 2008–2012 | 0.83 (0.58 to 1.19) | 1.51 (1.06 to 2.15) | 1.25 (0.98 to 1.61) | |||
| Yr 1a | ||||||
| 1996–2002 | 0.67 (0.31 to 1.49) | 1.49 (0.69 to 3.21) | 1.19 (0.62 to 2.26) | |||
| 2003–2007 (ref) | 1 | 1 | 1 | |||
| 2008–2012 | 0.71 (0.43 to 1.20) | 2.45 (1.78 to 3.39) | 1.84 (1.41 to 2.38) | |||
ref, referent group; 95% CI, 95% confidence interval.
a
Adjusted for age, sex, race, body mass, vascular access type, dialysis vintage, home hemodialysis modality, region, facility size, distance, income quintile, primary diagnosis, diabetes, coronary artery disease, stroke, peripheral vascular disease, and smoking status.