Table 7.
Air Pollution and Carotid Artery Disease
| Author | Study | N | Air Pollutants | Summary |
|---|---|---|---|---|
| Kunzli et al., 2010 [87] | Ambient air pollution and the progression of atherosclerosis in adults | 1483 | Road proximity and PM2.5 | Increase in CIMT |
| Newman et al., 2015 [88] | Particulate air pollution and carotid artery stenosis | 307,444 | PM2.5 | An independent risk factor for carotid artery stiffness |
| Wang et al., 2016 [89] | Residential Proximity to Traffic-Related Pollution and Atherosclerosis in 4 Vascular Beds Among African-American Adults: Results From the Jackson Heart Study | 4,800 | Road proximity | African Americans show increase in CIMT |
| Akintoye et al., 2016 [90] | Association between fine particulate matter exposure and subclinical atherosclerosis: A meta-analysis | 11,947 | PM2.5 | CIMT values within range of adverse cardiovascular events |
| Provost et al., 2016 [91] | Short-term fluctuations in personal black carbon exposure are associated with rapid changes in carotid arterial stiffening | 54 | Black carbon | Short term elevations associated with carotid artery stiffness |
| Perez et al., 2015 [92] | Air pollution and atherosclerosis: a cross-sectional analysis of four European cohort studies in the ESCAPE study | 9,183 | Road proximity and PM2.5 | Positive, but non-significant associations with increased CIMT |
| Gan et al., 2014 [93] | Long-term exposure to traffic-related air pollution and progression of carotid artery atherosclerosis: a prospective cohort study | 509 | black carbon, fine particles, nitrogen dioxide and nitric oxide | No association with carotid artery atherosclerosis |
| Breton et al., 2016 [95] | Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults | 768 | PM2.5 and O3 | Prenatal exposure, increases in carotid artery stiffness |
| Breton et al., 2012 [96] | Childhood air pollutant exposure and carotid artery intima-media thickness in young adults | 861 | PM2.5 and O3 | Prenatal exposure, increases in CIMT |
| Iannuzzi et al., 2010 [97] | Air pollution and carotid arterial stiffness in children | 52 | Road proximity | Increases in carotid artery stiffness |
| Adar et al., 2013 [98] | Fine particulate air pollution and the progression of carotid intima-medial thickness: a prospective cohort study from the multi-ethnic study of atherosclerosis and air pollution | 5,660 | PM2.5 | Reductions slowed CIMT progression |
| Wilker et al., 2013 [99] | Long-term exposure to black carbon and carotid intima-media thickness: the normative aging study | 380 | Black carbon | Increase in CIMT in elderly men |