Table 2. Hazard ratios (HRs) and 95% confidence interval (CIs) for all-cause mortality and breast cancer specific mortality in relation to depression^*.

	n	Cases	Model 1a		Model 2b		Model 3c		Model 4d
			HR	95% CI	HR	95% CI	HR	95% CI	HR	95% CI
All-cause mortality
Baseline analysis
Depression
No	2738	476	1		1		1		1
Yes	357	66	1.31	0.98-1.74	1.22	0.91-1.62	1.13	0.84-1.52	1.07	0.79-1.44
Year three analysis
Depression
No	2709	469	1		1		1		1
Yes	386	73	1.49	1.13-1.95	1.37	1.04-1.80	1.32	1.00-1.75	1.35	1.02-1.78
Breast cancer mortality
Baseline analysis
Depression
No	2738	165	1		1		1		1
Yes	357	22	1.03	0.62-1.70	1.01	0.60-1.67	0.87	0.50-1.50	0.76	0.44-1.32
Year three analysis
Depression
No	2709	158	1		1		1		1
Yes	386	29	1.48	0.95-2.30	1.45	0.93-2.26	1.39	0.87-2.19	1.39	0.87-2.20

^aResults were adjusted for age.

^bResults were adjusted for age, race, body mass index, smoking.

^cResults were adjusted for age, race, body mass index, smoking, history of postmenopausal hormone therapy, comorbidity, mammography use, tumor stage.

^dResults were adjusted for age, race, body mass index, smoking, history of postmenopausal hormone therapy, comorbidity, mammography use, tumor stage, tumor grade, and estrogen receptor & progesterone receptor status.

^*“Depression” includes depressive symptoms or anti-depressant use.