Table 2.
Clinical parameters by quartiles of Mechanical Dyssynchrony
| All | Dyssynchrony as assessed by SD T2P LS in the 4CH view T2P quartiles
|
|||||
|---|---|---|---|---|---|---|
| n=424 | Quartile 1 n=106 | Quartile 2 n=109 | Quartile 3n=103 | Quartile 4 n=106 | P for trend | |
|
| ||||||
| T2P (ms) | 59.0 [39.5, 88.5] | <39.5 | 39.5–59.0 | 59.1–88.5 | >88.5 | |
| Demographics | ||||||
| Age (years) | 70.2 ± 9.8 | 69.8 ± 9.5 | 69.0 ± 10.4 | 69.7 ± 9.2 | 72.4 ± 9.7 | 0.044 |
| Women, n (%) | 231 (54.5%) | 55 (51.9%) | 71 (65.1%) | 55 (53.4%) | 50 (47.2%) | 0.23 |
| White, n (%) | 339 (80.0%) | 88 (83.0%) | 87 (79.8%) | 77 (74.8%) | 87 (82.1%) | 0.66 |
| Enrollment in Russia/Georgia, n (%) | 105 (24.8%) | 32 (30.2%) | 29 (26.6%) | 18 (17.5%) | 26 (24.5%) | 0.17 |
| Clinical | ||||||
| Enrollment strata: previous hospitalization, n (%) | 271 (63.9%) | 76 (71.7%) | 69 (63.3%) | 65 (63.1%) | 61 (57.5%) | 0.041 |
| Myocardial Infarction, n (%) | 111 (26.2%) | 22 (21.0%) | 24 (22.0%) | 28 (27.2%) | 37 (34.9%) | 0.014 |
| Coronary revascularization, n (%) | 126 (29.8%) | 27 (25.7%) | 35 (32.1%) | 22 (21.4%) | 42 (39.6%) | 0.12 |
| Stroke, n (%) | 43 (10.2%) | 8 (7.6%) | 15 (13.8%) | 9 (8.7%) | 11 (10.4%) | 0.81 |
| Atrial fibrillation, n (%) | 176 (41.6%) | 46 (43.8%) | 47 (43.1%) | 39 (37.9%) | 44 (41.5%) | 0.57 |
| Diabetes mellitus, n (%) | 161 (38.1%) | 39 (37.1%) | 41 (37.6%) | 37 (35.9%) | 44 (41.5%) | 0.59 |
| Hypertension, n (%) | 389 (92.0%) | 96 (91.4%) | 100 (91.7%) | 94 (91.3%) | 99 (93.4%) | 0.65 |
| NYHA functional class (3 & 4), n (%) | 161 (38.2%) | 43 (41.0%) | 45 (41.7%) | 34 (33.0%) | 39 (36.8%) | 0.32 |
| QRS Duration (ms) | 100.9 ± 27.1 | 90.8 ± 17.3 | 98.5 ± 22.9 | 102.6 ± 28.3 | 111.4 ± 33.2 | <0.001 |
| QRS duration > 120 ms | 84 (19.8%) | 8 (7.5%) | 18 (16.5%) | 21 (20.4%) | 37 (34.9%) | <0.001 |
| BMI (kg/m2) | 32.5 ± 6.9 | 32.1 ± 6.3 | 33.6 ± 7.7 | 33.1 ± 6.8 | 31.1 ± 6.6 | 0.26 |
| Heart Rate (beats per minute) | 68.7 ± 10.8 | 68.7 ± 10.3 | 69.7 ± 11.6 | 67.3 ± 10.6 | 69.0 ± 10.6 | 0.75 |
| Systolic blood pressure (mmHg) | 126.5 ± 15.2 | 124.3 ± 13.3 | 127.1 ± 14.3 | 128.4 ± 17.5 | 126.3 ± 15.3 | 0.27 |
| Diastolic blood pressure (mmHg) | 72.6 ± 10.8 | 72.7 ± 11.2 | 73.5 ± 9.8 | 71.0 ± 11.0 | 73.1 ± 11.0 | 0.79 |
| Lab work | ||||||
| Creatinine (mg/dL) | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.4 | 1.2 ± 0.4 | 1.1 ± 0.3 | 0.47 |
| Z score BNP | −0.1 ± 1.0 | −0.1 ± 1.2 | −0.2 ± 0.9 | 0.1 ± 0.9 | 0.2 ± 0.9 | 0.041 |