Table 6.

Mechanical Dyssynchrony as assessed by SD T2P LS and the association with outcome in patients with and without atrial fibrillation

	N	Events	Hazard Ratio (95% CI)	P-value
In patients with sinus rhythm
SD T2P LS obtained from the 4CH view per 10 ms increase
Unadjusted	247	60	1.04 (0.99–1.08)	0.096
Model 1	247	60	1.02 (0.98–1.07)	0.273
Model 2	239	58	1.03 (0.98–1.08)	0.275
In patients with atrial fibrillation
SD T2P LS obtained from the 4CH view per 10 ms increase
Unadjusted	176	47	1.04 (0.99–1.08)	0.098
Model 1	176	47	1.03 (1.00–1.08)	0.129
Model 2	171	47	1.02 (0.96–1.07)	0.526
Interaction between SD T2P LS and atrial fibrillation
Unadjusted				0.940
In fully adjusted model (Model 2)				0.154

Model 1 is adjusted for age, sex, race, randomization strata (previous HF hospitalization or biomarker criteria), randomized treatment. Model 2 includes the same variables as Model 1 + core laboratory left ventricular LVEF, heart rate, New York Heart Association class, history of stroke, creatinine, hematocrit and QRS duration.