Table 3.
Characteristics of Hispanic patients (N=1933)
| Variable | Hispanic White | Hispanic Black | Hispanic Others | P-value |
|---|---|---|---|---|
| Number of enrolled patients | 1590 | 64 | 279 | |
| Number of centers | 102 | 32 | 54 | |
| Patient-related variables | ||||
| Median age at transplant, year | 57 (19–75) | 57 (40–74) | 57 (28–74) | 0.46 |
| <45 | 184 (12) | 4 (6) | 25 (9) | |
| 45–60 | 793 (50) | 32 (50) | 147 (53) | |
| 61–75 | 613 (39) | 28 (44) | 107 (38) | |
| Sex, Male | 907 (57) | 30 (47) | 160 (57) | 0.27 |
| Karnofsky Score <90% | 621 (39) | 28 (44) | 101 (36) | 0.72 |
| HCT-CI index | 0.09 | |||
| No comorbidity | 502 (32) | 19 (30) | 97 (35) | |
| 1–2 | 524 (33) | 15 (23) | 100 (36) | |
| ≥ 3 | 381 (24) | 23 (36) | 61 (22) | |
| Missing | 183 (12) | 7 (11) | 21 (8) | |
| Clinical Trial Enrollment | 51 (3) | 1 (2) | 13 (5) | 0.33 |
| Disease-related variables | ||||
| Immunochemical subtype | 0.67 | |||
| IgG | 862 (54) | 36 (56) | 157 (56) | |
| IgA | 340 (21) | 11 (17) | 59 (21) | |
| Light chain | 332 (21) | 15 (23) | 52 (19) | |
| Non-secretory | 35 (2) | 2 (3) | 4 (1) | |
| Others | 21 (1) | 0 | 7 (3) | |
| ISS/DSS III | 934 (59) | 35 (55) | 131 (47) | 0.008 |
| Time from diagnosis to transplant | 0.52 | |||
| < 6 months | 369 (23) | 12 (19) | 55 (20) | |
| 6 – 12 months | 711 (45) | 26 (41) | 123 (44) | |
| > 12 months | 508 (32) | 26 (41) | 100 (36) | |
| Missing | 2 | 0 | 1 | |
| Transplant-related variables | ||||
| Melphalan dose 200 mg/m2 | 1336 (84) | 51 (80) | 249 (89) | 0.04 |
| Disease status prior transplant | 0.98 | |||
| sCR/CR | 259 (16) | 10 (16) | 46 (16) | |
| VGPR | 499 (31) | 18 (28) | 94 (34) | |
| PR | 653 (41) | 27 (42) | 107 (38) | |
| SD/Relapse/Progression | 172 (11) | 9 (14) | 31 (11) | |
| Missing | 7 (<1) | 0 | 1 (<1) | |
| Planned post-transplant therapy | 0.03 | |||
| No | 1294 (81) | 60 (94) | 217 (78) | |
| Yes | 295 (19) | 4 (6) | 61 (22) | |
| Missing | 1 (<1) | 0 | 1 (<1) | |
| Median follow-up of survivors (range), months | 37 (1–99) | 37 (4–74) | 25 (1–82) |
Abbreviations: HCT-CI, hematopoietic cell transplantation-comorbidity index; ISS, International Staging System; DSS, Durie-Salmon Staging; CR, complete response; VGPR, very good partial response; PR, partial response; SD, stable disease