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. 2017 Aug 4;7:7345. doi: 10.1038/s41598-017-07433-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Induction of pulmonary cytokine/chemokine responses in immunocompetent and immunocompromised mice inoculated with influenza B viruses. BALB/c, NOD scid, and BALB scid mice were inoculated with viruses as described in the legend for Fig. 2. The expression levels of 25 cytokines and chemokines were assayed in lung homogenates at 3 and 9 dpi. Bars represent mean values ± SE (n = 5–6/group/time-point). ^* P < 0.05, relative to PH/13; ^# P < 0.05, relative to MA/12; and ^† P < 0.05, relative to BR/08, as determined by one-way ANOVA with Bonferroni’s multiple comparison post-test.