. 2017 Jul 21;19(7):e264. doi: 10.2196/jmir.6743

Table 3.

Comparison of lung function between the two groups before and after intervention with repeated data analysis of variance.

Item and group		Baseline	After intervention (month)				F_2,4	P
			1	3	6	12
FEV₁%
	Intervention, mean (SD)	0.38 (1.16)	0.41 (0.18)	0.41 (0.18)	0.41 (0.19)	0.42 (0.20)	2.324	.08
	Control, mean (SD)	0.33 (0.14)	0.33 (0.16)	0.32 (0.16)	0.31 (0.15)^b	0.30 (0.15)^a,b,c,d	4.863	.01
	t₁	1.881	1.486	2.811	2.872	3.622
	P	.06	.14	.01	.01	<.001
FVC%
	Intervention, mean (SD)	0.50 (0.17)	0.55 (0.18)^a	0.56 (0.18)^a	0.57 (0.18)^a	0.56 (0.18)^a	5.509	.001
	Control, mean (SD)	0.47 (0.19)	0.50 (0.16)^a	0.48 (0.16)	0.47 (0.16)^b	0.46 (0.14)^d	3.533	.01
	t₁	1.730	1.486	2.934	3.191	3.507
	P	.32	.14	.004	.002	.001
PEF
	Intervention, mean (SD)	0.32 (0.16)	0.39 (0.19)^a	0.41 (0.20)^a	0.43 (0.20)^a,b	0.41 (0.19)^a	12.486	<.001
	Control, mean (SD)	0.28 (0.13)	0.27 (0.16)	0.29 (0.18)	0.29 (0.17)	0.27 (0.16)	0.686	.56
	t₁	1.766	3.680	3.614	4.228	3.680
	P	.08	<.001	<.001	<.001	<.001
MEF_75% FVC
	Intervention, mean (SD)	0.22 (0.17)	0.23 (0.19)	0.25 (0.21)	0.25 (0.19)	0.25 (0.19)	2.397	.06
	Control, mean (SD)	0.17 (0.13)	0.19 (0.17)	0.18 (0.17)	0.17 (0.15)	0.15 (0.12)	0.606	.18
	t₁	1.669	1.341	2.103	2.468	3.369
	P	.10	.18	.04	.01	.001
MEF_50% FVC
	Intervention, mean (SD)	0.18 (0.17)	0.19 (0.15)	0.19 (0.14)	0.19 (0.15)	0.21 (0.16)	1.809	.15
	Control, mean (SD)	0.15 (0.15)	0.14 (0.13)	0.15 (0.15)	0.14 (0.13)	0.13 (0.10)	0.932	.42
	t₁	0.941	1.737	1.601	1.812	3.230
	P	.35	.08	.11	.07	.002
MEF_25% FVC
	Intervention, mean (SD)	0.18 (0.15)	0.22 (0.17)^a	0.23 (0.16)^a	0.21 (0.15)^a	0.22 (0.16)^a	2.861	.04
	Control, mean (SD)	0.16 (0.13)	0.18 (0.13)	0.20 (0.18)^a	0.17 (0.12)^c	0.17 (0.12)	2.611	.048
	t₁	0.865	1.388	0.913	1.418	1.789
	P	.39	.17	.36	.16	.08
MMEF
	Intervention, mean (SD)	0.18 (0.15)	0.20 (0.16)	0.21 (0.15)^a	0.20 (0.15)	0.22 (0.15)^a,d	3.180	.03
	Control, mean (SD)	0.15 (0.12)	0.16 (0.14)	0.18 (0.17)	0.16 (0.13)	0.15 (0.12)	1.766	.16
	t₁	1.275	1.395	1.187	1.577	2.621
	P	.20	.17	.24	.12	.01

^a Significant compared to baseline.

^b Significant compared to 1 month.

^c Significant compared to 3 months.

^d Significant compared to 6 months.