Table 1. Effects of methylation mutations on patterns of PAI promoter cytosine methylationa.
| Strain |
PAI gene |
CMeG |
CMeNG |
Other CMe |
Total CMe |
| WS | PAI1 | 236 (100%) | 127 (100%) | 298 (100%) | 661 (100%) |
| WSddm1 | PAI1 | 201 (85%) | 104 (81%) | 176 (60%) | 481 (73%) |
| WSmet1 | PAI1 | 61 (26%) | 52 (41%) | 142 (48%) | 255 (39%) |
| WS | PAI2 | 245 (100%) | 112 (100%) | 341 (100%) | 698 (100%) |
| WSddm1 | PAI2 | 123 (50%) | 27 (24%) | 76 (22%) | 226 (32%) |
| WS met1 | PAI2 | 131 (53%) | 44 (39%) | 136 (40%) | 311 (45%) |
aNumbers represent the indicated type of methylated cytosines for eight independent top strand plus eight independent bottom strand bisulfite sequencing clones for the indicated PAI promoter region of the indicated strain. The same data are shown in diagram form in Figure 2.