Table 2.
Predicted Effector | Ortholog Clade Distributiona | Paralog Clade Distributionb | Totalc | Paralogs in wMeld | Correlated Ortholog Treese | Pfam Domains? |
---|---|---|---|---|---|---|
WD0292 | A6 | A90,B88,F5 | 183 | WD0385**, C:4, wMel:1 | WD0290*, WD1171*, C:2, H:4, wMel:21 | Ankyrin |
WD0353 | A8 | A25,B14,F2 | 41 | wMel:1 | wMel:1 | IncA Zip |
WD1171 | A10 | A20,B17,D2,F1 | 40 | C:1 | WD0290*, WD0292*, C:1, wMel:6 | DUF3534 |
WD0811 | A10 | A9,B3,C2,D1,F1 | 16 | – | C:2 | – |
WD0385 | A7,B6 | A210,B322,D5,F21 | 558 | WD0292**, C:13, wMel:1 | C:1, other:42 | Ankyrin |
WalE1 | A8,B9 | A13,B9,C2,D1,F1 | 26 | – | C:13, H:7, wMel:61, other:37 | Synuclein |
WD0338 | A9,B8 | A31,B50,D4,F2 | 87 | C:1, wMel:1 | WD0462*, C:45, H:90, wMel:278, other:29 | – |
WD0462 | A9,B9 | A37,B19,F1 | 57 | C:1, wMel:1 | WD0338*, C:2, wMel:5, other:27 | IncA HAUS-augmin3 |
WD1321 | A11,B9 | A10,B9,D1 | 20 | – | C:1, wMel:2, other:30 | – |
WD0033 | A8,F1 | A18,B17,F1 | 36 | C:1, wMel:1 | C:2, H:5, wMel:19, other:3 | PAZ |
WD0290 | A6,B4,F1 | A16,B4,F1 | 21 | – | WD0292*, WD1171*, C:3, wMel:8, other:1 | DUF2207 IncA PAZ |
WD0465 | A7,C2,F1 | A11,B21,C2,F1 | 35 | – | – | DUF812 |
WD0438 | A10,B8,D1,F1 | A21,B18,D2,F3 | 44 | C:1 | C:1, wMel:6, other:1 | Ankyrin |
WD1223 | A10,B9,C2,D1,F1 | A11,B9,C2,D1,F1 | 24 | – | C:3, wMel:16, other:12 | – |
Note.—Column 2: The number of strains per supergroup in which this ortholog group is found. Column 3: The number of genes per supergroup that are homologous to this gene. Column 6: Ortholog groups with significantly correlated intraortholog pairwise distances with those of the predicted effector’s distances, based on p-mirrortree. See Materials and Methods.
The numbers after the supergroup letter is the number of strains matching in that supergroup. See figure 4 for supergroup clusters.
The numbers after the supergroup letter is the number of genes matching in that supergroup.
Sum of paralogs in previous column.
wMel genes with BLAST e-value ≤ 1e−6, percent identity ≥ 20, and overlap ≥ 30. *: predicted effector locus, C: candidate effector count, wMel: similarity to other wMel genes.
Orthologs with correlation significance P ≤ 0.05. *: predicted effector locus in correlated tree, C: other candidate effector ortholog count, H: wMel housekeeping gene, wMel: other wMel ortholog count, other: count of non-wMel containing orthologs.