Table 1.
Groups | Bacterial titer, 24 hpi [log10 CFU mL−1] | Change of weight | Neurological scoresa | Mortality |
---|---|---|---|---|
Sham | – | −2.64 ± 0.46 | 5 [5, 5] | 0/10 |
PBS + PM | 7.97 ± 0.50 | 1.50 ± 0.39* | 3 [3, 4]* | 4/14 |
DMSO + PM | 7.87 ± 0.42 | 1.37 ± 0.45* | 3 [3, 4]* | 3/14 |
BDNF + PM | 7.35 ± 0.41** | 1.08 ± 0.36*,** | 4 [3, 4]*, ** | 2/14 |
k252a + PM | 8.08 ± 0.27*** | 2.28 ± 1.40*, *** | 3 [3, 4]*, *** | 5/14 |
Bacterial titer, change of weight, neurological scores, and mortality were evaluated at 24 h post-infection
*p < 0.05, compared to sham group
**p < 0.05, compared to PBS + PM group
***p < 0.05, compared to BDNF + PM group
aMedian [minimum, maximum]