Table 1.
The identified succinylated proteins related to pathogenicity in fungi
| Protein names | Speciesa | Protein accessions | Succinylated lysine sites |
|---|---|---|---|
| 14–3-3 family protein | C. albicans | TERG_01614T0 | K51 |
| TERG_01614T1 | K28 | ||
| TERG_06816T0 | K49, K117, K122 | ||
| ABC multidrug transporter Mdr2 | T. rubrum, C. albicans, A. nidulans | TERG_06399T0 | K361, K368 |
| ABC transporter | C. albicans, A. fumigatus, C. neoformans, etc. | TERG_04224T0 | K12 |
| Aminopeptidase | T. rubrum, A. benhamiae, M. canis, A. fumigatus | TERG_06767T0 | K645 |
| TERG_06767T2 | K272, K518 | ||
| TERG_12154T0 | K680, K946 | ||
| Hsp60-like protein | C. albicans, H. capsulatum | TERG_04141T0 | K48, K75, K89, K130, K277, K282, K430, K437 |
| AhpC/TSA family thioredoxin peroxidase | A. fumigatus, C. albicans, C. neoformans | TERG_05504T0 | K66, K142 |
| Aspartic endopeptidase Pep2 | A. benhamiae, M. canis, C. albicans, A. fumigatus | TERG_06704T2 | K163 |
| Calnexin | A. fumigatus | TERG_07527T0 | K155, K203 |
| Catalase | A. nidulans, C. albicans, C. neoformans | TERG_02005T0 | K491 |
| Glutathione S-transferase GstA | A. fumigatus | TERG_00370T0 | K202 |
| G-protein complex beta subunit CpcB | C. heterostrophus, V. dahliae | TERG_00783T0 | K56 |
| Heat shock protein 70 (Hsp70) | C. albicans, H. capsulatum, C. neoformans | TERG_03206T1 | K37, K58, K137, K165, K222, K223, K276, K302, K331, K528, K545, K571 |
| TERG_06505T0 | K91, K157, K244, K326, K422, K511 | ||
| TERG_06505T2 | K422 | ||
| TERG_03037T0 | K134, K102, K131, K323, K367 | ||
| TERG_01002T0 | K482 | ||
| TERG_01883T0 | K361 | ||
| Leucine aminopeptidase 1 | T. rubrum, A. benhamiae, M. canis, A. oryzae, A. fumigatus | TERG_05652T0 | K116 |
| Leucine aminopeptidase 2 | T. rubrum, A. benhamiae, M. canis, A. oryzae, A. fumigatus | TERG_08405T1 | K17, K46, K380, K416 |
| Subtilisin-like protease | A. fumigatus, T. rubrum, A. benhamiae, M. canis and other dermatophyte species | TERG_12591T0 | K255 |
| Malate synthase AcuE | C. albicans, A. benhamiae | TERG_01281T0 | K161, K319, K483, K486, K501 |
| Molecular chaperone Mod-E/Hsp90 | F. graminearum, C. albicans, A. fumigatus | TERG_06963T0 | K171, K382, K385, K436, K479, K515, K550, K559, K565 |
| Peptidase S41 family protein | A. fumigatus, T. rubrum, A. benhamiae, M. canis | TERG_08195T1 | K490 |
| Peptidyl-prolyl cis-trans isomerase | C. albicans, C. neoformans | TERG_01573T0 | K36, K75, K120, K113 |
| TERG_06858T0 | K67, K75, K88, K126 | ||
| Probable chaperone protein Hsp31 homologue, putative | C. albicans | TERG_00228T0 | K159 |
| Rho GTPase Rho1 | C. albicans, C. neoformans | TERG_07578T0 | K155 |
| Rho-gdp dissociation inhibitor | C. neoformans | TERG_05090T3 | K125 |
| TERG_05090T4 | K122 | ||
| TERG_05090T5 | K125 | ||
| Tripeptidyl peptidase SED2 | A. fumigatus, T. rubrum | TERG_00619T0 | K340 |
| carboxypeptidase S1, putative | T. rubrum, A. benhamiae, M. canis, A. fumigatus | TERG_08255T1 | K490 |
aThe column “Species” indicates the organisms in which the proteins involved in pathogenicity have been reported