Table 1.

Baseline demographic, clinical, and pathologic characteristics and their univariable association with OS.

Characteristic		Median OS, years (95% CI)	HR (95% CI)	p-value*
Median age at diagnosis (range)	60 (39–84)
Median cm maximum tumor dimension (range)	9 (2–25)	NA		0.976
No. sex (%)				0.145
Male	116 (69.5)	4.07 (0.38–3.27)	0.74 (0.49–1.11)
Female	51 (30.5)	3.06 (0.43–2.01)	1.00
No. race (%)				0.698
White	139 (83.2)	2.93 (0.2–2.17)	1.48 (0.2–10.68)
Other	3 (1.8)	3.89 (1.64–1.57)	1.00
NA	25 (15)
No. primary tumor laterality (%)				0.272
Left	80 (47.9)	4.11 (0.47–3.29)	1.00
Right	79 (47.3)	3.44 (0.37–2.32)	1.25 (0.84–1.86)
NA	8 (4.8)
No. primary tumor grade (%)				<0.001
2	30 (18)	5.25 (0.67–5.24)	1.00
3	62 (37.1)	4.4 (0.55–3.66)	1.38 (0.75–2.57)
4	75 (44.9)	2.57 (0.32–1.57)	2.66 (1.5–4.72)
No. T stage (%)				0.412
T1	16 (9.6)	4.69 (0.92–3.41)	1.00
T2	20 (12)	4.88 (0.86–6.1)	1.04 (0.42–2.59)
T3	112 (67.1)	3.47 (0.33–2.17)	1.58 (0.76–3.29)
T4	15 (9)	3.47 (0.82–2.79)	1.46 (0.57–3.72)
NA	4 (2.4)
No. N stage (%)				0.086
N0	75 (44.9)	3.92 (0.45–2.54)	1.00
N1	24 (14.4)	2.53 (0.58–1.19)	1.65 (0.95–2.86)
NX	64 (38.3)	3.92 (0.39–3.39)	0.89 (0.58–1.37)
NA	4 (2.4)
No. KPS (%)				0.652
60	2 (1.2)	4.12 (1.4–4.12)	1.00
70	4 (2.4)	2.71 (0.6–3.41)	1.73 (0.23–13.11)
80	11 (6.6)	4.18 (0.71–4.45)	0.65 (0.12–3.6)
90	18 (10.8)	3.52 (0.63–3.95)	1.08 (0.21–5.47)
100	11 (6.6)	4.27 (0.68–NA)	0.56 (0.1–3.12)
NA	121 (72.5)
No. size				0.245
< 7 cm	44 (26.3)	4.2 (0.59–3.39)	1.00
≥ 7 cm	123 (73.7)	3.53 (0.33–2.08)	1.31 (0.83–2.07)

^*p-value from log-rank test.