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Frequency of gene mutations overall, with univariable associations between mutations and OS.
| Characteristic | No. (%) | HR (95% CI) | p-value |
|---|---|---|---|
| VHL | 0.268 | ||
| WT | 65 (38.9) | 1 | |
| Mut | 102 (61.1) | 0.80 (0.54–1.18) | |
| PBRM1 | 0.494 | ||
| WT | 103 (61.7) | 1 | |
| Mut | 64 (38.3) | 0.87 (0.59–1.29) | |
| BAP1 | 0.008 | ||
| WT | 138 (82.6) | 1 | |
| Mut | 29 (17.4) | 1.85 (1.17–2.92) | |
| SETD2 | 0.027 | ||
| WT | 129 (77.2) | 1 | |
| Mut | 38 (22.8) | 0.58 (0.35–0.94) | |
| KDM5C | 0.019 | ||
| WT | 142 (85) | 1 | |
| Mut | 25 (15) | 0.45 (0.23–0.89) |
