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. 2017 Aug 5;16:314. doi: 10.1186/s12936-017-1958-x

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Inter-laboratory variability is reduced when potency relative to the reference reagent 10/198 replaces direct measurement. Box histograms show ELISA derived values for 1/EC₅₀ (left) and potency (right) for samples C1, C2, C3 and XC from each laboratory (1–16) with AMA-1 as the coating antigen (a), MSP-1₄₂ as the coating antigen (b), and MSP-3 (c)