Table 1.
Clinico-demographic characteristics across demographically-matched diagnostic groups.
| Neurologically normal older adults (n=91) (a) | Alzheimer’s disease (n=566) (b) | Logopenic variant PPA (n=34) (c) | Behavioral variant FTD (n=97) (d) | Semantic variant PPA (n=71) (e) | Nonfluent variant PPA (n=39) (f) | p-value | |
|---|---|---|---|---|---|---|---|
| Neuroimaging within 90 days | n=56 | n=86 | n=20 | n=36 | n=36 | n=25 | |
| Age, y | 66.0 (8.4) | 66.6 (8.5) | 64.5 (7.7) | 65.2 (6.7) | 64.7 (7.4) | 68.1 (6.3) | 0.13 |
| Education, y | 16.7 (2.6) | 15.9 (2.8) | 16.5 (2.8) | 16.1 (2.5) | 16.3 (2.7) | 16.0 (2.4) | 0.12 |
| Sex (%M, n) | 44.0% (40) | 45.1% (255) | 57.9% (18) | 57.3% (55) | 54.9% (39) | 46.2% (18) | 0.19 |
| Total MMSE | 29.2 (1.0) | 23.8 (3.2) | 23.2 (3.3) | 25.5 (3.0) | 25.5 (3.0) | 26.4 (2.0) | < 0.001 a > b–f; d–f > b,c |
Note. PPA = primary progressive aphasia; FTD = frontotemporal dementia; MMSE = Mini-Mental Status Exam.