In patient 2, fused images obtained at B1 hours show mild 68Ga-DOTAF(ab′)2-trastuzumab uptake in a lung metastasis (arrows). 68Ga-DOTA-F(ab′)2- trastuzumab, 68Ga-1,4,7,10-tetraazacyclododecane-N,N′,N′,N‴-tetraacetic acid (DOTA)-F(ab′′)2-trastuzumab. (From Beyergil V, Morris PG, Smith-Jones PM, et al. Pilot study of 68Ga-DOTA-F(ab′)2-trastuzumab in patients with breast cancer. Nucl Med Commun 2013; 34(12):1163; with permission.)