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. Author manuscript; available in PMC: 2018 Aug 15.
Published in final edited form as: Arch Biochem Biophys. 2017 Mar 2;628:123–131. doi: 10.1016/j.abb.2017.02.009

Figure 1. Biochemical network involving glucose metabolism.

Figure 1

Glucose is oxidized to pyruvate (glycolysis). Several intermediates are involved in parallel and intersecting pathways: glycogen metabolism, pentose phosphate pathway, serine pathways, lipid biosynthesis and the Krebs Cycle. G6P: glucose-6-phosphate; F6P fructose-6-phosphate; F1,6BP fructose-1,6-bisphosphate; GAP glyceraldehyde-3-phosphate; DHAP dihydroxyacetone phosphate; 1,3bisPG 1,3-bisphosphoglycerate; 2PGA 2-phosphogycerate; PEP phosphoenolpyruvate; Pyr pyruvate; OAA oxaloacetate; AcCoA acetyl CoA; Lac lactate; Ru5P ribose-5-phosphate; HK hexokinase; G6Pase glucose-6-phosphatase; PGI phosphoglucose isomerase; PFK1 phosphofructokinase 1; FBPase fructose 1,6 bisphosphatase; ALD aldolase; GAPDH glyceraldehyde-3- phosphate dehydrogenase; PGK phosphoglycerate kinase; PGM phosphoglycerate mutase; ENO enolase; PK pyruvate kinase; LDH lactate dehydrogenase; ALT alanine transaminase; PC pyruvate carboxylase; PDH pyruvate dehydrogenase; PPPox oxidative branch of the pentose phosphate pathway; PPPnx non-oxidative branch of the pentose phosphate pathway. Adapted from [12] “With permission of Springer”.