Table 1.

Steady-state kinetic parameters for ATP-PRT inhibition in the presence of TIH

	[TIH] (mM)
Parameters	0	0.25	0.8	4
V max (s−1)	0.21 ± 0.01	0.28 ± 0.01	0.38 ± 0.01	0.76 ± 0.01
K m,ATP (mM)	0.23 ± 0.03	0.20 ± 0.02	0.18 ± 0.02	0.16 ± 0.02
K i,ATP (mM)	20 ± 1	25 ± 1	41 ± 2	89 ± 5