FIGURE 2.

A lung-on-a-chip created by culturing human alveolar epithelial cells and pulmonary microvascular endothelial cells

A: a lung-on-a-chip created by culturing human alveolar epithelial cells and pulmonary microvascular endothelial cells on opposing sides of a porous membrane. B: the system could recreate organ-level functions, such as an inflammatory response bacteria. C: the system was also used as a model for lung diseases like pulmonary edema. Reprinted from Ref. 33, with permission from Nature Reviews Drug Discovery.