Table 1. Effectiveness of the study luteolin formulation in ASDs children with high serum IL-6 and TNF levels (n=10).
| Vineland adaptive behavior scales (VABS) | 0 week | 26 week | Change | Effect sizea | P-value |
|---|---|---|---|---|---|
| Communication AE | 38.91 (25.47)b | 48.64 (31.60) | 9.73 | 0.38 | 0.008 |
| Daily living skills AE | 38.45 (19.11) | 45.09 (21.00) | 6.64 | 0.35 | 0.0003 |
| Social AE | 36.55 (18.04) | 44.64 (20.93) | 8.09 | 0.45 | 0.001 |
| Composite score | 37.97 (19.68) | 46.12 (23.19) | 8.15 | 0.42 | 0.001 |
Abbreviations: AE, age equivalent; ASD, autism spectrum disorder; IL, interleukin; TNF, tumor necrosis factor; VABS, Vineland Adaptive Behavior Scale.
a
(26 week–0 week)/0 week s.d.
b
VABS scores (s.d.).