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. 2016 Jul 26;6(7):e860. doi: 10.1038/tp.2016.125

Figure 3.

Figure 3

Autistic features in Df(h15q13)−/− mice. (a) Mice were placed in individual cages and observed for 10 min. Quantification of repetitive jumping or crawling in the corner of the cage is shown here. n=10–13 for each genotype, female mice. Kruskal–Wallis test, P<0.05. Dunn’s multiple comparisons indicated. (b) Three-chambered social approach task. Social sniffing: time spent sniffing the cylinder with the novel mouse. Total sniffing time: time spent sniffing the cylinder with the novel mouse and the empty cylinder. n=6–7 females for each genotype. One-way ANOVA, P<0.01. Tukey’s multiple comparisons indicated. (c) Ultrasonic vocalization in 6-day-old pups. Calls are normalized to the average number of calls within each litter. n=6–53 for each genotype. One-way ANOVA, P<0.05. Tukey’s multiple comparisons indicated. Data presented as mean±s.e.m. *P<0.05; **P<0.01. ANOVA, analysis of variance; WT, wildtype.