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Box plots of CSF biomarkers (a) total tau (P<0.001), (b) p-tau (P<0.001), (c) FABP3 (p0 0.044) and (d) neurogranin (P=0.009) Neurogranin, comparing those with low (< 530 pg ml−1) and high (> 530 pg ml−1) CSF Aβ42 (42 amino acid form of β-amyloid). Aβ42, amyloid β 42; CSF, cerebrospinal fluid; FABP3, fatty acid binding protein-3; p-tau, tau phosphorylated at 181.
