Table 3. Top canonical pathways enriched in BD patients as recognised by ingenuity pathway analysis at iPSC and NSC stages, respectively.

Name	P-value
Top canonical pathways at iPSC stage
TREM1 signalling	0.00376
Top canonical pathways at NSC stage
Intrinsic prothrombin activation pathway	0.0179
GABA receptor signalling	0.0418
TREM1 signalling	0.0442
Dopamine receptor signalling	0.0486

Abbreviations: BD, bipolar disorder; iPSC, induced pluripotent stem cell; NSC, neural stem cell; TREM1, triggering receptor expressed on myeloid cells 1.