. Author manuscript; available in PMC: 2017 Aug 7.

Published in final edited form as: Blood Purif. 2012 Oct 24;34(2):138–148. doi: 10.1159/000342129

Table 1.

Pediatric studies of fluid overload at the time of CRRT initiation and mortality

Author	Year	Patient number and design	Outcome

Selewski et al. [64]	2011	113 patients	Increased fluid overload associated with increased mortality, independent of illness severity score and other clinical factors in patients on ECMO and general pediatric critical care
Selewski et al. [64]	2011	Single-center, retrospective study

Sutherland et al. [65]	2010	297 patients	Fluid overload >20% associated with increased mortality independent of illness severity and other clinical factors
Sutherland et al. [65]	2010	Multicenter, prospective observational study

Hayes et al. [66]	2009	76 patients	Fluid overload >20% associated with increased mortality independent of illness severity and other clinical factors
Hayes et al. [66]	2009	Single-center, retrospective study

Goldstein et al. [67]	2005	116 patients	Fluid overload >20% associated with increased mortality independent of illnesses severity and other clinical factors
Goldstein et al. [67]	2005	Multicenter, prospective observational study

Gillespie et al. [68]	2004	77 patients	Fluid overload >10% was associated with increased mortality independent of illness severity and other clinical factors
Gillespie et al. [68]	2004	Single-center, retrospective study

Foland et al. [69]	2004	113 patients	Increased fluid overload associated with increased mortality independent of illness severity score and other clinical factors
Foland et al. [69]	2004	Single-center, retrospective study

Goldstein et al. [70]	2001	21 patients	Fluid overload at CRRT initiation was associated with increased mortality independent of illness severity score
Goldstein et al. [70]	2001	Single-center study