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. 2017 Jul 29;8(6):607–616. doi: 10.1016/j.jare.2017.07.005

Table 2.

Permeation flux (%/h) values of TDF from non-everted and everted intestine sac permeation study.

Parameter TDF permeation from non-everted intestine sac
TDF permeation from everted intestine sac
Absence of enzyme
Presence of enzyme
Absence of enzyme
Presence of enzyme
TDF solution TDF loaded LCP TDF solution TDF loaded LCP TDF solution TDF loaded LCP TDF solution TDF loaded LCP
Permeation flux (%/h) 3.41 ± 0.21 17.45 ± 1.34** 3.62 ± 0.37 ns 21.86 ± 1.0** 3.07 ± 1.03 11.94 ± 1.28** 3.70 ± 1.34 ns 16.86 ± 1.34**
Apparent permeation coefficient (cm/h)2 2.17 ± 1.04 11.11 ± 2.2** 2.3 ± 1.11 ns 13.91 ± 2.31** 1.95 ± 1.27 7.6 ± 1.57** 2.35 ± 1.18 ns 10.73 ± 1.84**

Mean ± SD. Data analyzed by one way ANOVA followed by posthoc Dunnett’s test, with *P < 0.05 considered significant, **P < 0.01, ns – nonsignificant, n = 3.