Table 5.

Association of GRSs with plasma HDL-C^a level by study groups.

	Hungarian General		Hungarian Roma
	β (95% CI)	p-value	β (95% CI)	p-value
GRS
Model I	−0.01 (−0.018 to −0.003)	0.004	−0.013 (−0.023 to −0.003)	0.011
Model II	−0.011 (−0.018 to −0.004)	0.003	−0.013 (−0.023 to −0.003)	0.009
wGRS
Model III	−0.243 (−0.466 to −0.020)	0.033	−0.318 (−0.633 to −0.002)	0.049
Model IV	−0.205 (−0.420 to 0.101)	0.062	−0.336 (−0.651 to −0.21)	0.036

The association of GRS and wGRS with plasma HDL-C level were evaluated under unadjusted regression models (Model I and III) and under regression models adjusted for age and sex (Model II and IV) separately in Roma and general subjects. In all models the HDL-C was the dependent variable, the GRS/wGRS were the independent variables.

95% CI: 95% confidence interval

^aHDL-C values were non-normally distributed and were transformed using a two-step approach suggested by Templeton [4].