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(A) Tumor volume and (B) mice body weight changes after treatment with saline, DOX, T1k2k, T1k2k-TOS, and T1k2k-TOS-DOX. Data are presented as mean ± SD (n = 6) (C) survival curves of mice after different treatments (n = 5). (D) Histological analysis (H&E staining) of tumor, liver, and heart tissues after treatment with saline, DOX, T1k2k, T1k2k-TOS, and T1k2k-TOS-DOX.
