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. Author manuscript; available in PMC: 2017 Aug 7.
Published in final edited form as: J Med Chem. 2006 Dec 28;49(26):7836–7842. doi: 10.1021/jm060803i

Figure 4.

Figure 4

Induction of G0/G1 cell cycle arrest in LNCaP cells. Cells were treated with vehicle (control) or 50 nM of either 1, 2, 3 or DOX for 72 h. Cell cycle distribution was determined by PI staining and flow cytometry. (A) Histograms of cell cycle distribution, and (B) mean cell cycle distribution (%) in the G0/G1, S and G2/M phases of three independent experiments ± SEM. *, P < 0.05; **, P < 0.0001 by ANOVA.