Table 2.
Summary of strain-dependent differences in STR, ERG, and UHR-OCT data (LE = Long-Evans, BN = Brown Norway, SD = Sprague-Dawley). Letters ‘a’, ‘b’, and ‘c’ represent significant differences between other strains.
| Component | Treated Eye | Control Eye | ||||
|---|---|---|---|---|---|---|
| Prior to IOP elevation | During IOP elevation | Post IOP | Prior to IOP elevation | During IOP elevation | Post IOP | |
| STR amplitudes | none | LE(a)=BN(a)>SD(b) | none | none | ||
| STR implicit times | none | LE(a)<BN(b)=SD(b) | none | none | ||
| ERG-a wave amplitudes | none | LE(a)=BN(a)>SD(b) | none | none | ||
| ERG a-wave implicit times | none | LE(a)=BN(a)>SD(b) | none | none | ||
| ERG b-wave amplitudes | none | LE(a)=BN(a)>SD(b) | none | none | ||
| ERG b-wave implicit times | none | LE(a)=BN(a)<SD(b) | none | none | ||
| OP1, OP4 amplitudes | none | |||||
| OP1, OP4 implicit times | none | |||||
| OP2 amplitudes | LE(a)=BN(a)>SD(b) | |||||
| OP2 implicit times | none | |||||
| OP3 amplitudes * | BN(a)>LE(b)=SD(b) | LE(a)=BN(a)>SD(b) | BN(a)>LE(b)=SD(b) | LE(a)=BN(a)>SD(b) | ||
| OP3 implicit times | none | |||||
| OP5 amplitudes | none | |||||
| OP5 implicit times | none | BN(a)>LE(b)=SD(b) | none | none | ||
| xBMO | none | |||||
| GCC Thickness | LE(a)>BN(b)>SD(c) | n/a | LE(a)>BN(b)>SD(c) | n/a | ||
| Total Retinal Thickness | LE(a)>BN(b)=SD(b) | n/a | LE(a)>BN(b)=SD(b) | n/a | ||
*
no differences were observed between eyes for all loop conditions