Systematic name
|
Gene
|
Function
|
Phenotype
|
Ref.
|
| YAL051W |
OAF1 (YAF1) |
Activator of peroxisome
proliferation along with Oaf2p |
Impaired in growth
of oleate as a carbon source, induction of β-oxidation
enzymes is abolished |
19 |
| YBL005W |
PDR3 |
Activator related
to Pdr1p |
Pleiotropic drug
resistance |
6,46
|
| YBL066C |
SEF1 |
Suppressor of essential
function |
Defective sporulation;
high copy number suppressor of RPM2 |
47 |
| YBR033W |
– |
Unknown |
Unknown |
– |
| YBR150C |
– |
Unknown |
Unknown |
– |
| YBR239C |
– |
Unknown |
Unknown |
– |
| YBR240C |
THI2 (PHO6) |
Activator of thiamin
biosynthetic genes |
Thiamin auxotrophy,
reduced expression of thiamin biosynthetic genes |
41 |
| YBR297W |
MAL3R (MAL33) |
Part of complex locus
MAL3; MAL activator protein |
Defective maltose
fermentation |
48,49
|
| YCR106W |
– |
Unknown |
Unknown |
– |
| YDL170W |
UGA3 |
Activator necessary
for GABA-dependent function of GABA genes |
Exhibits defects
in activation of UGA1 and UGA4 |
50,51
|
| YDR034C |
LYS14 |
Transcriptional activator
of lysine pathway genes |
Lysine requiring |
52,53
|
| YDR207C |
UME6 |
Regulator of both
repression and induction of early meiotic genes |
Exhibits defects
in IME1-dependent activation and repression |
54 |
| YDR213W |
UPC2 |
Involved in sterol
uptake |
upc2-1 allele shows
altered sterol uptake and increased sensitivity to NaCl and LiCl |
55,56
|
| YDR303C |
– |
Unknown |
Null mutant is inviable |
This study, 32,33
|
| YDR421W |
– |
Unknown |
Moderately sensitive
to SDS and benomyl |
45 |
| YDR520C |
– |
Unknown |
Slight caffeine sensitivity |
This study |
| YER184C |
– |
Unknown |
Unable to grow on
non-fermentable carbon sources; sensitive to calcofluor white |
This study |
| YFL052W |
– |
Unknown |
Unable to grow on
non-fermentable carbon sources; sensitive to calcofluor white; heat sensitive
on rich but not minimal medium |
This study |
| YGL013C |
PDR1 (CYH3) |
General positive
regulator of permeability genes |
Pleiotropic drug
resistance |
6,57
|
| YGR288W |
MAL13 |
Part of complex locus
MAL1; MAL activator protein (non-functional in S228C and derivatives) |
Defective maltose
fermentation |
48,49
|
| YHR178W |
STB5 |
Binds Sin3p in two-hybrid
assay |
Cold and caffeine
sensitive |
This study, 40
|
| YIL130W |
– |
Unknown |
Unable to grow on
non-fermentable carbon sources; sensitive to calcofluor white, cyclheximide,
benomyl, and MMS; slightly sensitive to hydoxyurea |
This study, 45
|
| YIR023W |
DAL81 (UGA35) |
Positive regulator
of multiple nitrogen catabolic genes such as allantoin and GABA
catabolic genes |
Unable to degrade
allantoin |
51,58,59
|
| YJL089W |
SIP4 |
Involved in Snf1p
regulated transcriptional activation |
Required for maximal
expression of carbon source responsive genes; moderate sensitivity
to SDS |
60,61,45
|
| YJL103C |
– |
Unknown |
Unknown |
– |
| YJL206C |
– |
Unknown |
Unknown |
– |
| YKL015W |
PUT3 |
Positive regulator
of PUT (proline utilization) genes |
Unable to use proline
as sole nitrogen source |
62,63
|
| YKL038W |
RGT1 |
Transcriptional repressor
and activator of genes involved in glucose metabolism |
Constitutive expression
of glucose-induced HXT genes; sensitive to calcofluor white; sensitive
to SDS, unable to grow on non–fermentable carbon source;
slight sensitivity to MMS |
11,45
|
| YKL222C |
– |
Unknown |
Moderately sensitive
to caffeine |
This study |
| YKR064W |
– |
Unknown |
Unknown |
– |
| YLL054C |
– |
Unknown |
Unable to grow on
non–fermentable carbon sources; sensitive to calcofluor
white |
This study |
| YLR014C |
PPR1 |
Activator of URA1
and URA3 |
Deficient in pyrimidine
biosynthetic pathway |
64,65
|
| YLR098C |
CHA4 (SIL2) |
Activator of CHA1 |
Unable to grow with
serine or threonine as sole nitrogen source |
66 |
| YLR228C |
ECM22 |
Unknown |
Moderately sensitive
to caffeine |
This study, 42
|
| YLR256W |
HAP1 (CYP1) |
Activator of respiration
genes |
Essential for anaerobic
or heme deficient growth; sensitive to SDS and EGTA; moderately
sensitive to hygromycin |
4,5,45
|
| YLR266C |
– |
Unknown |
Unable to grow on
non-fermentable carbon sources; sensitive to calcofluor white |
This study |
| YLR278C |
– |
Unknown |
Moderately sensitive
to caffeine |
This study |
| YLR451W |
LEU3 |
Regulates expression
of genes involved in branched chain amino acid biosynthesis and ammonia
assimilation |
Leaky leucine auxotroph |
67,68
|
| YML076C |
– |
Unknown |
Unknown |
– |
| YML099C |
ARG81 (ARGR2) |
Positive and negative
regulator of many arginine-responsive genes |
|
69 |
| YMR019W |
STB4 |
Binds Sin3p in two-hybrid
assay |
Sensitive to caffeine |
This study, 40,45
|
| YMR168C |
CEP3 |
Cbf3 kinetochore
complex binds CDE III centromere element |
Essential gene |
35,36
|
| YMR280C |
CAT8 |
Involved in activation
of gluconeogenic genes |
Unable to grow on
non-fermentable carbon sources and ethanol |
70 |
| YNR063W |
– |
Unknown |
Unknown |
– |
| YOL089C |
HAL9 |
Involved in salt
tolerance |
Exhibits decreased
salt tolerance and ENA1 expression |
71 |
| YOR162C |
YRR1 |
Activator of multi-drug
resistance genes |
Hypersensitive to
4-nitroquinoline oxide (4-NQO) and benomyl; unable to grow on non-fermentable
carbon sources; sensitive to calcofluor white |
This study, 39,45
|
| YOR172W |
– |
Unknown |
Unknown |
– |
| YOR337W |
TEA1 |
Activator of Ty1
elements |
Diminished Ty1 expression;
sensitive to SDS and moderately sensitive to MMS |
72,45
|
| YOR363C |
OAF2 (PIP2) |
Activator of peroxisome
proliferation along with Oaf1p |
Impaired in growth
of oleate as a carbon source, induction of β-oxidation
enzymes is abolished |
19,73
|
| YOR380W |
– |
Unknown |
Unable to grow on
non-fermentable carbon sources; sensitive to calcofluor white |
This study |
| YPL133C |
– |
Unknown |
Unable to grow on
non-fermentable carbon sources; sensitive to calcofluor white |
This study |
| YPL248C |
GAL4 |
Activator of GAL
genes |
Cannot utilize galactose
as sole carbon source |
3 |
| YPR094W |
– |
Unknown |
Unknown |
– |
| YPR196W |
MAL63 |
Activator of maltose genes |
Unable to ferment maltose |
48,49
|
