Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 7;8:917. doi: 10.3389/fimmu.2017.00917

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Fu, Han, Xie, Li, Lin, Pan, Zhou, Li, Jin and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Actin enhances neutrophil activation through triggering receptor expressed on myeloid cells-1 (TREM-1) signaling. (A) RAW264.7 cells were treated with LPS for 4 h and further incubated with rACTIN and LP17 for an additional 5 h. Then, the supernatants were collected for detection of TNF-α concentration with a commercial ELISA kit (n = 6). (B) Peritoneal macrophages isolated from trem1^+/+ or trem1^−/− mice (n = 6) were treated with LPS for 4 h and further incubated with rACTIN and LP17 for an additional 5 h. Finally, the supernatants of the cells were collected for the detection of TNF-α, IL-6, and MCP-1 concentration with commercial ELISA kits. The data were expressed the means ± SE of measurement. *p < 0.05.