Table 1.
Isoform | 1000 × khyd | Low | High | t½ |
---|---|---|---|---|
min−1 | min | |||
H-Ras | 16 ± 3 | 13 | 19 | 40 |
K-Ras | 6 ± 1 | 4 | 7 | 120 |
N-Ras | 6 ± 2 | 4 | 8 | 120 |
H-Ras + Raf | 14 ± 2 | 12 | 15 | 50 |
K-Ras + Raf | 11 ± 1 | 10 | 13 | 60 |
N-Ras + Raf | 6 ± 1 | 5 | 7 | 120 |
H-RasQ95L | 19 ± 3 | 17 | 22 | 40 |
H-RasH166Y | 19 ± 1 | 18 | 20 | 40 |
H-RasY141F | 15 ± 1 | 14 | 16 | 50 |