. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: J Empir Res Hum Res Ethics. 2017 Apr 16;12(3):131–139. doi: 10.1177/1556264617704294

Table 1. Generalized linear regression of CCTS regulatory support receipt and covariates on turnaround time measures: August 2008 – June 2014 (N=3,526).

	Total Turnaround Time		IRB Processing and Review Time		PI Response Time

Predictor	b	SE_b	b	SE_b	b	SE_b
CCTS Regulatory Support Received (1=yes)	-1.40	4.37	1.48	2.31	-2.78	2.97
Year Application First Submitted	-1.82^***	0.37	-2.37^***	0.17	0.58^*	0.28
Investigator from College of Medicine (1=yes)	6.46^***	1.32	2.44^***	0.66	4.19^***	0.96
IRB Review Level (‘Full’ as reference)
Exempt	-41.1^***	2.84	-27.4^***	1.22	-13.9^***	2.07
Expedited	-28.6^***	2.75	-19.4^***	1.17	-9.26^***	1.98
Multisite Application (1=yes)	-0.45	1.44	-0.61	0.75	0.18	1.08
Protocol Modifications Required (1=yes)	33.3^***	1.01	12.3^***	0.63	20.9^***	0.66

p < 0.05;

^**

p < 0.01;

^***

p < 0.001

Note: CCTS – Center for Clinical and Translational Science. IRB – Institutional Review Board. PI – principal investigator. SE – standard error.