Table 2. Generalized linear regression of CCTS regulatory support level and covariates on turnaround time measures: August 2008 – June 2014 (N=88).

	Total Turnaround Time		IRB Processing and Review Time		PI Response Time
Predictor	b	SEb	b	SEb	b	SEb
Received More Intensive Regulatory Support (1=yes)	-16.0*	7.62	-4.25	4.43	-7.97	5.00
Year Application First Submitted	-5.97**	1.93	-4.47***	1.04	-1.35	1.40
Investigator from College of Medicine (1=yes)	6.90	6.50	1.25	3.22	4.44	5.04
IRB Review Level (‘Full’ as reference)
Exempt	-44.9***	8.76	-27.3***	5.52	-15.3**	5.64
Expedited	-9.27	7.05	-8.55*	3.80	0.99	5.50
Multi-Site Application (1=yes)	-3.93	6.33	3.28	3.98	-6.39	3.32
Protocol Modifications Required (1=yes)	35.9***	6.81	16.8***	4.21	18.8***	3.39

^*p < 0.05;

^**p < 0.01;

^***p < 0.001

Note: CCTS – Center for Clinical and Translational Science. IRB – Institutional Review Board. PI – principal investigator. SE – standard error.