Table 2.
Demographic and clinical characteristics of study subjects.
| Measure | OCD (N=16) | SIB (N=16) | CON (N=16) | f-Value | p-Value |
|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | |||
| Age (years) | 25.8 (6.0) | 27.1 (7.2) | 23.3 (5.8) | 1.85 | 0.17 |
| Male/female | 11/5 | 9/7 | 12/4 | 0.52 | |
| Education (years) | 13.0 (2.5) | 14.8 (2.5) | 12.8 (4.0) | 2.07 | 0.14 |
| IQ estimate | 102.4 (12.4) | 108.6 (13.5) | 110.3 (9.8) | 1.92 | 0.16 |
| Age at onset of OCD (years) | 18.5 (4.1) | ||||
| Duration of illness (years) | 7.4 (6.4) | ||||
| Y–BOCS (total) | 29.8 (6.4) | 9.1 (3.6) | 2.7 (2.1) | 164.06 | <0.01a,b,c |
| Y–BOCS (obsessions) | 15.9 (7.3) | 4.4 (2.1) | 1.7 (1.7) | 44.81 | <0.01a,c |
| Y–BOCS (compulsions) | 14.0 (3.5) | 4.6 (2.0) | 1.0 (1.1) | 123.80 | <0.01a,b,c |
| OCI-R | 20.1 (6.8) | 8.8 (3.7) | 12.3 (6.5) | 15.67 | <0.01a,c |
| BDI | 11.6 (12.9) | 5.9 (4.2) | 4.2 (3.6) | 3.63 | 0.04a |
| STAI (state) | 39.8 (7.3) | 37.8 (15.2) | 42.3 (4.7) | 0.82 | 0.45 |
| STAI (trait) | 40.4 (6.2) | 37.5 (15.6) | 39.9 (5.2) | 0.38 | 0.69 |
Abbreviations: BDI, Beck Depression Inventory; CON, healthy control subjects; OCD, patients with obsessive–compulsive disorder; OCI-R, Obsessive–Compulsive Inventory-Revised; SD, standard deviation; SIB, siblings of individuals with OCD; STAI, State-Trait Anxiety Inventory; Y–BOCS, Yale–Brown Obsessive–Compulsive Scale. a–c: Statistically significant values after Tukey post-hoc test between
a
OCD × CON.
b
SIB × CON.
c
OCD × SIB.