Fig. 7.

- Phospho-proteomics reveals Vpr-modulated kinase motifs. A, Comparison of Inducible HIV with data from the Wojcechowskyj et al. data set shows a 1081 protein overlap for proteins with identified phosphorylation sites. B, Within the 1081 proteins, 1477 phospho-sites were identified as being the same between the two data sets. Previously annotated motifs show an enrichment for cell cycle associated domains. C, Motif analysis of phospho-peptides shows differential WT-leaning motifs (Higher in WT than ΔVPR) and ΔVPR-Leaning motifs (Higher in ΔVPR than WT). Full motif analysis can be found in supplemental Figs. S9–S14 and supplemental File S13.