Figure 2.
Virologic and immunologic response
Proportion of participants with HIV-1 RNA <50 and <200 copies/mL: Vertical bars are 95% Clopper-Pearson binomial confidence intervals. Intention-to-treat (ITT) analysis includes all participants regardless of treatment status, with missing HIV-1 RNA counted as failure. The as-treated denominator excludes participants who permanently discontinued ETR + TDF/FTC or had a missing HIV-1 RNA result.
Change in CD4+ count from baseline: Estimated median and 95% distribution-free confidence interval (vertical bars) are plotted at each study week. The intention-to-treat (ITT) analysis includes evaluable participants regardless of treatment status. The as-treated analysis excludes participants who permanently discontinued ETR + TDF/FTC before CD4+ count evaluation.