Table 2.
Resistance testing among virologic failures through Week 48
Subject ID | VF Week |
VL at baseline, copies/mL |
VL at VF confirmation, copies/mL |
Genotype status |
Resistance associated mutations |
---|---|---|---|---|---|
1 | 8 | 19,356 | 422 | Below test thresholda | |
2 | 8 | 195,146 | 190,339 | Discontinued study treatmentb | |
3 | 8 | 848,845 | 82,432 | Tested | E138K, Y181C, M230L, M184I, K219E, V75I |
4 | 24 | 442,363 | 104 | Below test thresholda | |
5 | 24 | 10,823 | 110 | Below test thresholda | |
6 | 24 | 65,193 | 727 | Missingc | |
7 | 36 | 78,146 | 834 | Tested | Y181C |
8 | 36 | 83,096 | 244 | Below test thresholda | |
9 | 36 | 260,951 | 64 | Below test thresholda | |
10 | 48 | 37,177 | 53 | Below test thresholda | |
11 | 48 | 21,942 | 3129 | Tested | E138K |
VL: viral load, VF: virologic failure
Viral load below 500 copies/mL threshold specified by laboratory for genotype assay.
Participant developed rash and discontinued study treatment during Week 2.
Participant discontinued study participation, no sample available for genotype.