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. Author manuscript; available in PMC: 2018 Aug 26.
Published in final edited form as: Biochem Biophys Res Commun. 2017 Jun 20;490(3):739–745. doi: 10.1016/j.bbrc.2017.06.111

Figure 4. The effects of IFN on STAT binding to the promoters of STAT3-regulated ISGs.

Figure 4

ChIP assays were carried out on extracts from control and IFN-treated STAT3-KO MEFs transfected with WT-STAT3 (Panel A), and WT-STAT3 or F705-STAT3 (Panel B) using the indicated antibodies for precipitation and primers that targeted the promoters of these STAT3-regulated ISGs. Similar results were obtained in at least three independent experiments.