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. Author manuscript; available in PMC: 2018 Apr 20.
Published in final edited form as: Cell. 2017 Apr 20;169(3):381–405. doi: 10.1016/j.cell.2017.04.001

Figure 2. Substrates and functions of the Akt signaling network.

Figure 2

Akt phosphorylates downstream substrates involved in the regulation of diverse cellular functions, including multifunctional substrates. A partial list of known substrates is shown. P indicates phosphorylation, with red and green denoting inhibitory and activating regulation, respectively.