Table 3. Adverse events.
| Event | Any grade | Grade 3-4 | ||
|---|---|---|---|---|
| No of Patients | % | No of Patients | % | |
| Cardio-renal | ||||
| Atrial fibrillation | 1 | 6% | ||
| Elevated creatinine | 5 | 28% | 1 | 6% |
| Elevated phosphate | 2 | 11% | ||
| Elevated glucose | 3 | 17% | ||
| Hypoalbuminemia | 2 | 11% | ||
| Hypokalemia | 3 | 17% | 1 | 6% |
| Hypomagnesemia | 3 | 17% | ||
| Hyponatremia | 2 | 11% | 1 | 6% |
| Hypophosphatemia | 2 | 11% | 1 | 6% |
| Constitutional | ||||
| Dehydration | 1 | 6% | ||
| Fatigue | 8 | 44% | 1 | 6% |
| Dermatologic | ||||
| Alopecia | 3 | 17% | ||
| Gastrointestinal | ||||
| Anorexia | 3 | 17% | ||
| Hematemesis | 2 | 11% | 1 | 6% |
| Hiccups | 1 | 6% | 1 | 6% |
| Diarrhea | 1 | 6% | ||
| Elevated liver function tests | 4 | 22% | 1 | 6% |
| Hematochezia | 1 | 6% | ||
| Nausea or vomiting | 12 | 67% | 1 | 6% |
| HEENT | ||||
| Epistaxis | 2 | 11% | 2 | 11% |
| Hematologic | ||||
| Anemia | 14 | 78% | 4 | 22% |
| Elevated PT/PTT | 4 | 22% | 4 | 22% |
| Bleeding or bruising | 1 | 6% | ||
| Lymphopenia | 15 | 83% | 13 | 72% |
| Myelodysplastic Syndrome | 2 | 11% | 2 | 11% |
| Neutropenia | 16 | 89% | 16 | 89% |
| Thrombocytopenia | 12 | 67% | 1 | 6% |
| Infectious | ||||
| Sepsis | 1 | 6% | ||
| Febrile neutropenia | 4 | 22% | 4 | 22% |
| Fever | 2 | 11% | ||
| Neurologic | ||||
| Subdural hematoma | 1 | 6% | 1 | 6% |