Table 2. Tests of between-subjects effects dependent variable: MMSE score progression.
| Source | Type III sum of squares | Significant |
|---|---|---|
| Age | 6.37 | 0.099 |
| Sex | 0.017 | 0.932 |
| APOE ε2 gene carrying | 0.162 | 0.791 |
| APOE ε4 gene carrying | 0.539 | 0.63 |
| Frontal lobe WMH volume | 0.085 | 0.848 |
| Number of lacunes | 0.56 | 0.623 |
| dPVS grade in centrum ovale | 1.901 | 0.366 |
| dPVS in basal ganglia | 0.406 | 0.676 |
| HBP score | 0.089 | 0.844 |
| APOE ε2 × dPVS in basal ganglia | 0.271 | 0.732 |
| APOE ε4 × dPVS in basal ganglia | 0.011 | 0.945 |
| APOE ε2 × dPVS in centrum ovale | 1.186 | 0.475 |
| APOE ε4 × dPVS in centrum ovale | 0.002 | 0.98 |
| APOE ε2 × Frontal lobe WMH volume | 0.605 | 0.609 |
| APOE ε4 × Frontal lobe WMH volume | 9.011 | 0.050* |
| APOE ε2 × lacune | 9.135 | 0.049* |
| APOE ε4 × lacune | 0.203 | 0.844 |
P<0.05 was considered statistical significant, the factors influencing MMSE progression.